研究領域：

本實驗室之研究重點為多並苯類化合物之合成與其在材料科學上之應用。 我們最近開發出了兩個十分有用的合成反應用於建構多並苯類結構。我們也合成出了一系列帶有多並苯類化結構單元的硫醇分子，將應用於含多並苯類化合物之自組裝單層薄膜。

1) 在多並苯類化合物上之(醚-醚)及(醚-硫醚)交換反應:

 

2) 以重複加長法合成多並苯類化合物:

 

 

3) 各類用於建構自組裝單層薄膜的多並苯類化合物硫醇分子:

 

代表作：

1. Lin, K.-H.; Pal, B.; Tsou, L.-D.; Lin, C.-H. Iterative Synthesis of Acene via Homo-elongation. Chem. Comm. 2009, 803.
   

2. Chen, J.-C.; Lee, T.-S.; Lin, C.-H. Syntheses of Ladder-Type Oligonaphthalene Derivatives and Their
   Photophysical and Electrochemical Properties. Chem. Eur. J. 2008, 14, 2777.
   

3. Tseng, Y. P.; Kuo, Y. H.; Hu, C. P.; Jeng, K. S.; D. Janmanchi, D.; Lin, C. H.; Chou, C. K.; Yeh, S. F. The Role of Helioxanthin in Inhibiting Human Hepatitis B Viral Replication and Gene Expression by Interfering with the Host Transcrioptional Machinery. Antiviral Res. 2008, 77, 206.
   

4. Tseng, P.-C.; Hsu, H.-C.; Janmanchi, D.; Lin, C.-H.; Kuo, Y.-H.; Chou, C.-K.; Yeh, S.-F. The Role of Helioxanthin in Inhibiting Interleukin-1β-induced MIP-1β Production in Human Hepatoma Cells by Reduction of c-Jun Expression and Subsequent Binding of the c-jun/CREB1 Complex to the AP-1/CRE Site of the MIP-1β Promoter. Biochem. Pharma. 2008, 76, 1121.

5. Lin, Y. C.; Lin, C. H. Synthesis of tetracene sulfoxide and tetracene sulfone via a cascade cyclization reaction. Org. Lett. 2007, 9, 2075.

6. Yang, H.-C.; Lin, S.-M.; Liu, Y.-H.; Wang, Y.; Chen, M.-M.; Sheu, H.-S.; Tsou, D.-L.; Lin, C-H.; Luh, T.-Y. Ring Opening Metathesis Polymerization of Bisnorbornene Derivatives Linked by Cp2Ni2(m-S)2 Bridge. J. Organometallic Chem. 2006, 691, 3196.

7. Radhakrishnan K; Lin, C-H. Synthesis of anthryl sulfides from anthryl methyl ethers via acid-catalyzed ether-sulfide exchange reaction. Synlett 2005, 14, 2179

8. Lin, C-H.; Radhakrishnan K. Synthesis of anthracene ethers from anthracene methyl ethers via an acid-catalyzed exchange reaction. Chem. Comm. 2005, 4, 504

9. Lin, C-H.; Tour, J. Hydrogen-Bond-Assisted p-Stacking of Shape-Persistent Cyclophanes. J. Org. Chem. 2002, 67, 7761.

Update： 2010-02-06