Luo, Fen-Tair

Metallo-Organic Chemistry, Supertorrefaction and Supergasification, Catalysis, Organic Synthesis

Luo, Fen-Tair (羅芬臺)

    886-2-27898576
    886-2-27831237
    luoft
Research Fellow (1991-);Joint Research Fellow, Institute of Astronomy and Astrophysics of Academia Sinica (2015-);B.S., Soochow University(l975);M.S., National Tsing Hua University (1980);Ph.D., Purdue University (1984);Postdoctoral Research Fellow, Stanford University (1984-85);Associate Research Fellow, Academia Sinica (1985-91). Member, Chinese Chemical Society and American Chemical Society. ;
Research Interests

1. Design and Synthesis of Polymer-supported Palladium Catalyst
2. Hydrogen Production from Biomass
3. Supertorrefaction and Supergasification of Biomass in Molten Salts
4. Use Microfluidic System in Organic Synthesis
5. Synthesis of Water-soluble BODIPY-based Fluorescent Probes



Selected Publications
  1. Zhang, J.; Li, C.; Dutta, C.; Fang, M.; Zhang, S.; Tiwari, A.; Werner, T.; Luo, F.-T.; Liu, H. A Novel Near-infrared Fluorescent Probe for Sensitive Detection of β-Galactosidase in Living Cells. Analytica Chimica Acta, 2017968, 97.
  2. Zhang, S.; Adhikari, R.; Fang, M.; Dorh, N.; Li, C.; Jaishi, M.; Zhang, J.; Tiwari, A.; Pati, R.; Luo, F.-T.; Liu, H. Near-Infrared Fluorescent Probes with Large Stokes Shifts for Sensing Zn(II) Ions in Living Cells. ACS Sensors20161, 1408.
  3. Zhang, J.; Yang, M.; Mazi, W.; Adhikari, K.; Fang, M.; Xie, F.; Valenzano, L.; Tiwari, A.; Luo, F.-T.; Liu, H. Unusual Fluorescent Responses of Morpholine-functionalized Fluorescent Probes to pH via Manipulation of BODIPY’s HOMO and LUMO Energy Orbitals for Intracellular pH Detection. ACS Sensors 20161, 158.
  4. Dorh, N.; Zhu, S.; Dhungana, K. B.; Pati, R.; Luo, F.-T.; Liu, H.; Tiwari, A. BODIPY-Based Fluorescent Probes for Sensing Protein Surface-Hydrophobicity. Sci. Rep. 2015, 5, 18337.
  5. Zhang, J.; Yang, M.; Li, C.; Dorh, N.; Xie, F.; Luo, F.-T.; Tiwari, A.; Liu, H. Near-infrared Fluorescent Probes Based on Piperazine-Functionalized BODIPY Dyes for Sensitive Detection of Lysosomal pH. J. Mater. Chem. B, 2015, 3, 2173.
  6. Vegesna, G. K; Janjanam, J.; Bi, J.; Luo, F.-T.; Zhang, J.; Olds, C.; Tiwari, A.; Liu, H. pH-Activatable Near-Infrared Fluorescent Probes for Detection of Lysosomal pH inside Living Cells. J. Mater. Chem. B, 2014, 2, 4500.
  7. Liu, H.; Vegesna, G.; Sripathi, S.; Zhang, J.; Zhu, S.; Luo, F.-T.; Jahng, W. J.; Frost, M. Highly Water-soluble BODIPY-based Fluorescent Probe for Sensitive and Selective Detection of Nitric Oxide in Living Cells. ACS Applied Materials & Interfaces 2013, 5, 4107.
  8. Zhu, S.; Bi, J.; Vegesna, G.; Zhang, J.; Luo, F.-T.; Valenzano, L.; Liu, H. Functionalization of BODIPY Dyes at 2,6-Positions through Formyl Groups. RSC Adv. 2013, 3, 4793.
  9. Zhu, S.; Zhang, J.; Janjanam, J.; Dorh, N.; Bi, J.; Vegesna, G.; Luo, F.-T.; Tiwari, A.; Liu, H. Highly Water-soluble BODIPY-based Fluorescent Probes for Sensitive Fluorescent Sensing of Zinc(II). J. Mater. Chem. B 2013, 1, 1722.
  10. Zhang, J.; Zhu, S.; Valenzano, L.; Luo, F.-T.; Liu, H. BODIPY-based Ratiometric Fluorescent Probes for Sensitive and Selective Sensing of Cyanide Ion. RSC Adv. 2013, 3, 68.
  11. Zhu, S.; Zhang, J.; Janjanam, J.; Bi, J.; Vegesna, G.; Tiwari, A.; Luo, F.-T.; Wei, J.; Liu, H. Highly Water-soluble, Near-infrared Emissive BODIPY Polymeric Dye Bearing RGD Peptide Residues for Cancer Imaging. Analytica Chimica Acta 2013, 758, 138.
  12. Zhu, S.; Dorh, N.; Zhang, J.; Vegesna, G.; Li, H.; Luo, F.-T.; Tiwari, A.; Liu, H. Highly Water-soluble Neutral Near-infrared Emissive BODIPY Polymeric Dyes. J. Mater. Chem. 2012, 22, 2781.
  13. Lo, H.-K.; Luo, F.-T. Synthesis of PS-supported NHC-Pd catalyst derived from theobromine and its applications in Suzuki-Miyaura reaction. J. Chin. Chem. Soc. 2012, 59, 394.
  14. Zhu, S.; Zhang, J.; Vegesna, G.; Tiwari, A.; Luo, F.-T.; Zeller, M.; Luck, R.; Li, H.; Green, S.; Liu, H.; Controlled Knoevenagel Reactions of Methyl Groups of 1,3,5,7-Tetramethyl BODIPY Dyes for Unique BODIPY Dyes. RSC Adv. 2012, 2, 404.
  15. Zhu, S.; Zhang, J.; Vegesna, G. K.; Pandey, R.; Luo, F.-T.; Green, S.; Liu, H.; One-pot Efficient Synthesis of Dimeric, Trimeric, and Tetrameric BODIPY Dyes. Chem. Commun. 2011, 47, 3508.
  16. Zhu, S.; Zhang, J.; Vegesna, G.; Luo, F.-T.; Green, S.; Liu, H. Highly Water-soluble Neutral BODIPY Dyes with Controllable Fluorescence Quantum Yields. Org. Lett. 2011, 13, 438.
  17. Luo, F.-T.; Lo, H.-K. Synthesis of bis-NHC-Pd catalyst derived from caffeine and its applications in Suzuki, Heck, and Sonogashira reactions. J. Organomet. Chem. 2011, 696, 1262.

Selected Patent:

  1. Frank H. Shu, Fen-Tair Luo, Michael J. Cai, “Batch-Process Supertorrefaction System and Method”, Taiwan Patent, TW I560265, December 1, 2016.
  2. Frank H. Shu, Fen-Tair Luo, Michael J. Cai, “Batch-Process Supertorrefaction System and Method”, USA, Canada, China, Russia, India, Germany, France. WO2015171865 A1, November 12, 2015.
  3. Frank H. Shu, Michael J. Cai, Fen-Tair Luo, “Supertorrefaction of Biomass into Biocoal”, P. R. China Patent, CN 103249817 A, August 26, 2015.
  4. Frank H. Shu, Michael J. Cai, Fen-Tair Luo, “Supertorrefaction of Biomass into Biocoal”, USA Patent, US 9096800, August 4, 2015.
  5. Frank H. Shu, Michael J. Cai, Fen-Tair Luo, "Supertorrefaction of Biomass (Variants)", Russia Patent, No. 2549876, April 3, 2015.
  6. Frank H. Shu, Michael J. Cai, Fen-Tair Luo, “Supertorrefaction of Biomass into Biocoal”, “Supertorrefaction de Biomasse en Biocharbon (French)”, Canada Patent, CA 2807094, March 31, 2015.
  7. Frank H. Shu, Michael J. Cai, Fen-Tair Luo, “Supertorrefaction of Biomass into Biocoal”, Taiwan Patent, TW I443187, July 1, 2014.
  8. Fen-Tair Luo, “Polystyrene-supported Palladacycle Catalysts”, USA Patent, US 7115762 B2, October 3, 2006.

 

Update: 2017-05-09

Journal Paper
  1. Jianheng Bi, Mingxi Fang, Jianbo Wang,* Shuai Xia, Yibin Zhang, Jingtuo Zhang, Giri Vegesna, Shuwei Zhang, Marina Tanasova,* Fen-Tair Luo,* and Haiying Liu* Near-Infrared Fluorescent Probe for Sensitive Detection of Pb(II) Ions in Living Cells. Inorganica Chimica Acta 2017,.
  2. Shuwei Zhang, Rashmi Adhikari, Mingxi Fang, Nethaniah Dorh, Cong Li, Meghnath Jaishi, Jingtuo Zhang, Ashutosh Tiwari,* Ranjit Pati,* Fen-Tair Luo,* and Haiying Liu* Near-Infrared Fluorescent Probes with Large Stokes Shifts for Sensing Zn(II) Ions in Living Cells. ACS Sensors 2016-11-171, 1408-1415.
  3. Shuwei Zhang, Tzu-Ho Chen, Hsien-Ming Lee,* Jianheng Bi, Avik Ghosh, Mingxi Fang, Zichen Qian, Fei Xie, Fen-Tair Luo,* Feng Zhao,* Haiying Liu* Luminescent Probes for Sensitive Detection of pH Changes in Live Cells through Two Near-infrared Luminescence Channels. ACS Sensors 2017-06-272(7), 924-931.
  4. Jingtuo Zhang, Cong Li, Colina Dutta, Mingxi Fang, Shuwei Zhang, Ashutosh Tiwari,* Thomas Werner,* Fen-Tair Luo,* and Haiying Liu* A Novel Near-infrared Fluorescent Probe for Sensitive Detection of beta-Galactosidase in Living Cells. Analytica Chimica Acta 2017-05-22968, 97-104.
  5. Jingtuo Zhang, Mu Yang, Wafa Mazi, Kapil Adhikari, Mingxi Fang, Fei Xie, Loredana Valenzano,* Ashutosh Tiwari,* Fen-Tair Luo,* Haiying Liu* Unusual Fluorescent Responses of Morpholine-functionalized Fluorescent Probes to pH via Manipulation of BODIPY’s HOMO and LUMO Energy Orbitals for Intracellular pH Detection. ACS Sensors 2016-02-261, 158-165.
  6. Nethaniah Dorh, Shilei Zhu, Fen-Tair Luo, Haiying Liu, Ashutosh Tiwari BODIPY-Based Fluorescent Probes for Sensing Protein Surface-Hydrophobicity. Scientific Reports 2015-12-185, 18337.
  7. Jingtuo Zhang, Mu Yang, Cong Li, Nethaniah Dorh, Fei Xie, Fen-Tair Luo, Ashutosh Tiwari, and Haiying Liu Near-infrared Fluorescent Probes Based on Piperazine-Functionalized BODIPY Dyes for Sensitive Detection of Lysosomal pH. J. Mater. Chem. B 2015-023, 2173-2184.
  8. Giri K Vegesna, Jagadeesh Janjanam, Jianheng Bi, Fen-Tair Luo, Jingtuo Zhang, Connor Olds, Ashutosh Tiwari, and Haiying Liu pH-Activatable Near-Infrared Fluorescent Probes for Detection of Lysosomal pH inside Living Cells. J. Mater. Chem. B 2014-062, 4500-4508.
  9. Jingtuo Zhang, Shilei Zhu, Loredana Valenzano, Fen-Tair Luo, Haiying Liu BODIPY-based Ratiometric Fluorescent Probes for Sensitive and Selective Sensing of Cyanide Ion. RSC Adv. 20133, 68-72.
  10. Shilei Zhu, Jianheng Bi, Giri Vegesna, Jingtuo Zhang, Fen-Tair Luo, Loredana Valenzano and Haiying Liu Functionalization of BODIPY Dyes at 2,6-Positions through Formyl Groups. RSC Adv. 20133, 4793-4800.
  11. Liu, Haiying; Vegesna, Giri; Sripathi, Srinivas; Zhang, Jingtuo; Zhu, Shilei; Luo, Fen-Tair; Jahng, Wan Jin; Frost, Megan Highly Water-soluble BODIPY-based Fluorescent Probe for Sensitive and Selective Detection of Nitric Oxide in Living Cells. ACS Applied Materials & Interfaces 20135(10), 4107-4112.
  12. Shilei Zhu, Jingtuo Zhang, Jagadeesh Janjanam, Nethaniah Dorh, Jianheng Bi, Giri Vegesna, Fen-Tair Luo, Ashutosh Tiwari, and Haiying Liu Highly Water-soluble BODIPY-based Fluorescent Probes for Sensitive Fluorescent Sensing of Zinc (II). J. Mater. Chem. B 20131, 1722-1728.
  13. Shilei Zhu, Jingtuo Zhang, Jagadeesh Janjanam, Jianheng Bi, Giri Vegesna, Ashutosh Tiwari, Fen-Tair Luo, Jianjun Wei, and Haiying Liu Highly Water-soluble, Near-infrared Emissive BODIPY Polymeric Dye Bearing RGD Peptide Residues for Cancer Imaging. Analytica Chimica Acta 2013758(1), 138-144.
  14. Shilei Zhu, Jingtuo Zhang, Giri Vegesna, Ashutosh Tiwari, Fen-Tair Luo, Matthias Zeller, Rudy Luck, Haihua Li, Sarah Green and Haiying Liu Controlled Knoevenagel Reactions of Methyl Groups of 1,3,5,7-Tetramethyl BODIPY Dyes for Unique BODIPY Dyes. RSC Adv. 20122, 404-407.
  15. Shilei Zhu, Nethaniah Dorh, Jingtuo Zhang, Giri Vegesna, Haihua Li, Fen-Tair Luo, Ashutosh Tiwari and Haiying Liu Highly Water-soluble Neutral Near-infrared Emissive BODIPY Polymeric Dyes. J. Mater. Chem. 201222, 2781-2790.
  16. Hung-Kun Lo, Fen-Tair Luo Synthesis of PS-supported NHC-Pd catalyst derived from theobromine and its applications in Suzuki-Miyaura reaction. J. Chin. Chem. Soc. 201259(3), 394-398.
  17. Shilei Zhu, Jingtuo Zhang, Giri Vegesna, Fen-Tair Luo, Sarah Green and Haiying Liu Highly Water-soluble Neutral BODIPY Dyes with Controllable Fluorescence Quantum Yields. Organic Letters 201113, 438-441.
  18. Shilei Zhu, Jingtuo Zhang, Giri K. Vegesna, Ravi Pandey, Fen-Tair Luo, Sarah A. Green and Haiying Liu One-pot Efficient Synthesis of Dimeric, Trimeric, and Tetrameric BODIPY Dyes for Panchromatic Absorption. Chemical Communications 201147, 3508-3510.
  19. Fen-Tair Luo, Hung-Kun Lo Short Synthesis of Bis-NHC-Pd Catalyst Derived from Caffeine and Its Applications to Suzuki, Heck, and Sonogashira Reactions. Journal of Organometallic Chemistry 2011696, 1262-1265.
  20. Cuihua Xue, Shi-Hao Kung, Jian-Zhung Wu, Fen-Tair Luo Intramolecular Palladium-Catalyzed Cyclization of Alkenylboronate Prepared from Hydroboration of Terminal Acetylene and Its Application to the Stereoselective Synthesis of (E)-Doxepin. Tetrahedron 200864, 248-254.
  21. Hsien-Ren Liao, Yih-Jiun Lin, Yu-Ma Chou, Fen-Tair Luo, Bo-Cheng Wang Theoretical Study of Optical and Electronic Properties of p-Tterphenyls Containing Cyano Substituents as Promising Light Emitting Materials. Journal of Luminescence 2008128, 1373-1378.
  22. Cuihua Xue, Fen-Tair Luo, Haiying Liu Post-polymerization Functionalization Approach for Highly Water-soluble Well-defined Regioregular Head-to-Tail Glycopolythiophenes. Macromolecules 2007, 6863-6870.
  23. Luo, FT、Ravi, VK Polymer-Bound Palladium Catalyst in Carbon-Carbon Bond Formation. Huaxue 2006, 第64卷第1期,頁1-20.
  24. Xue, CH, Luo, FT, Chen, J and Liu, HY Synthesis and Biosensing Application of Highly Water-soluble and Cross-linkable Poly(p-phenyleneethynylene) Containing Osmium(II) Complex and Aldehyde Groups. Analytica Chimica Acta 2006569(no.1-2), 27-34.
  25. Luo, FT, Ravi, VK and Xue, CH The Novel Reaction of Ketones with o-Oxazoline-substituted Anilines. Tetrahedron 200662(40), 9365-9372.
  26. C.J. Wu, C. Xue, Y.M. Kuo and F.T. Luo Preparation and Photoluminescence of p-Terphenyl Derivatives Containing Cyano Groups. Tetrahedron 200561, 4735-4741.
  27. F.T. Luo, C. Xue, S.L. Ko, Y.D. Shao, J.C. Wu and Y.M. Kuo Preparation of Polystyrene-supported Soluble Palladacycle Catalyst for Heck and Suzuki Reactions. Tetrahedron 200561, 6040-6045.
  28. C. Xue, Z. Chen, Y. Wen, F.T. Luo, J. Chen and H. Liu Synthesis of Ferrocene-grafted Poly(p-phenylene-ethynylene)s and Control of Electro-chemical Behaviors of Their Thin Films. Langmuir 200521, 7860-7865.
  29. C. Xue, Z. Chen, F.T. Luo, K. Palaniappan, D.J. Chesney, J. Liu, J. Chen and H. Liu Synthesis of Water-soluble Electroactive Ferrocene-grafted Poly(p-phenylene-ethynylene) via Phase Transfer and Its Biosensing Application. Biomacromolecules 20056, 1810-1815.
  30. C. Xue and F.T. Luo Novel p-Phenylene-vinylene-dithienylene Type Copolymer: Potential Red-emitting Materials. Synthetic Metals 2004145, 67-73.
  31. Z. Chen, C. Xue, W. Shi, F.T. Luo, S. Green, J. Chen and H. Liu Novel Selective and Sensitive Fluorescent Sensors for Metal Ions Based on Manipulation of Side Chain Compositions of Poly(p-phenylene- ethynylene)s. Analytical Chemistry 200476, 6513-6518.
  32. C. Xue and F.T. Luo* Rapid Syntheses of Oligo(p-phenylene- ethynylene)s via Iterative Convergent Approach.. Tetrahedron 200460, 6285-6294.
  33. C. Xue and F.T. Luo The Synthesis and the X-Ray Structure of 1,4-Bis(2-{4-[2-(4-methylthiophenyl)ethynyl]phenyl}ethynyl)-2,5-dihexyloxybenzene. Journal of the Chinese Chemical Society 200451, 1411-1416.
  34. C. Xue and F.T. Luo Transformation of Amides into Esters by the Use of Chlorotrimethylsilane. Journal of the Chinese Chemical Society 200451, 359-362.
  35. A. A. M. Movahedi, S. Hakimelahi, J. Chamani, G.A. Khodarahmi, F. Hassanzadeh, F.T. Luo, T.W. Ly, K.S. Shia, C.F. Yen, M.L. Jain, R. Kulatheeswaran, C. Xue, M. Pasdar and G.H. Hakimelahi Design, Synthesis, and Anticancer Activity of Phosphonic Acid Diphosphate Derivative of Adenine-containing Butenolide and Its Water Soluble Derivatives of Paclitaxel with High Antitumor Activity. Bioorganic & Medicinal Chemistry 200311, 4303-4313.
  36. C. Xue and F.T. Luo Efficient and Rapid Synthesis of Oligo(p-phenylene-vinylene) via Iterative Coherent Approach. Journal of Organic Chemistry 200368, 4417-4421.
  37. T.Y. Lu, C. Xue and F.T. Luo Palladium-catalyzed Cross-coupling Reaction of Aryldioxaborolane with 2-Bromo-N,N-dimethylacetamide. Tetrahedron Letters 200344, 1587-1590.
  38. F.T. Luo, T.Y. Lu and C. Xue Palladium-catalyzed Stereoselective Synthesis of (E)-beta,gamma-Unsaturated Amides. Tetrahedron Letters 200344, 7249-7251.
  39. C.A. Lin and F.T. Luo Polystyrene-supported Soluble Palladacycle Catalyst as Recyclable Catalyst for Heck, Suzuki, and Sonogashira Reactions. Tetrahedron Letters 200344, 7565-7568.
  40. C. Xue and F.T. Luo Synthesis of Oligo(p-phenylene-vinylene-thienylene)s as Potential Red Light-emitting Materials. Tetrahedron 200359, 5193-5198.
  41. B.C. Wang, J.C. Chang, J.H. Pan, C. Xue and F.T. Luo Theoretical Investigation of Electroluminescent material 1,4-Distyrylbenzene Derivatives. Journal of Molecular Structure (Theochem) 2003636, 81-87.
  42. Gholam Hossein Hakimelahi, Kak-Shan Shia, Cuihua Xue, Shahram Hakimelahi, Ali A. Moosavi-Movahedi, Ali A. Saboury, Ali Khalafi-Nezhad, Mohammad N. Soltani-Rad, Valeriy Osyetrov, Kung-Pern Wang, Jyh-Hsiung Liao and Fen-Tair Luo Design, Synthesis, and Biological Evaluation of a Series of beta-Lactam-Based Prodrugs. Bioorganic & Medicinal Chemistry 200210, 3489-3498.
  43. Fen-Tair Luo, Yu-Tai Tao, Sheng-Li Ko, Chang-Hao Chuen, and Hui Chen Efficient Electroluminescent Material for Light-Emitting Diodes from 1,4-Distyrylbenzene Derivatives. Journal of Materials Chemistry 200212, 47-52.
  44. Tomo Sakanoue, Yasukiyo Ueda, Sheng-Li Ko, and Hui Chen, Fen-Tair Luo Fabrication and Characterization of Orientation-Controlled Alkoxy- and Cyano-Substituted Distyrylbenzene Derivatives in Thin Film. Molecular Crystal and Liquid Crystals 2002377, 153-156.
  45. Cuihua Xue, Fen-Tair Luo Synthesis of p-Phenylene-vinylene-thienylene Oligomers. Heterocycles 200257, 1935-1946.
Chapter of Publication
  1. Chih-An Lin, Fen-Tair Luo, 2004, “Polystyrene-Supported Soluble Palladacycle Catalyst as Recyclable Catalyst for Heck, Suzuki, and Sonogashira Reactions”, editor(s): S. M. Roberts, J. Whittall, P. Mather, and P. McCormack, Catalysts for Fine Chemical Synthesis, Vol. 3, Metal Catalysed Carbon-Carbon Bond-Forming Reactions, pp. 116-125, England: John Wiley & Sons.
  2. Fen-Tair Luo, 2002, “Other -Hetero-Substituted Organometals in Palladium-Catalyzed Cross-Coupling”, editor(s): Ei-ichi Negishi, Handbook of Organopalladium Chemistry for Organic Synthesis, Vol. 1, pp. 673-691, New York: John Wiley & Sons.
Science Report
  1. Tomo Sakanoue, Shuhei Nakatani, Yasukiyo Ueda, Fen-Tair Luo, 2002, “Structure and Optical Properties of Distyrylbenzene/PTFE Double Layer”, Technical Report of IEICE (The Institute of Electronics, Information and Communication Engineers), pp. 47, 1-6.