Luo, Fen-Tair

Metallo-Organic Chemistry, Supertorrefaction and Supergasification, Catalysis, Organic Synthesis

Luo, Fen-Tair (羅芬臺)

    886-2-27898576
    886-2-27831237
    luoft
Research Fellow (1991-);Joint Research Fellow, Institute of Astronomy and Astrophysics of Academia Sinica (2015-);B.S., Soochow University(l975);M.S., National Tsing Hua University (1980);Ph.D., Purdue University (1984);Postdoctoral Research Fellow, Stanford University (1984-85);Associate Research Fellow, Academia Sinica (1985-91). Member, Chinese Chemical Society and American Chemical Society. ;
Research Interests

1. Design and Synthesis of Polymer-supported Palladium Catalyst
2. Hydrogen Production from Biomass
3. Supertorrefaction and Supergasification of Biomass in Molten Salts
4. Use Microfluidic System in Organic Synthesis
5. Synthesis of Water-soluble BODIPY-based Fluorescent Probes



Selected Publications
  1. Bi, J.; Fang, M.; Wang, J.; Xia, S.; Zhang, Y.; Zhang, J.; Vegesna, G.; Zhang, S.; Tanasova, M.; Luo, F.-T.; Liu, H. Near-Infrared Fluorescent Probe for Sensitive Detection of Pb(II) Ions in Living Cells. Inorg. Chim. Acta, 2017, 468, 140.
  2. Zhang, S.; Chen, T.-H.; Lee, H.-M.; Bi, J.; Ghosh, A.; Fang, M.; Qian, Z.; Xie, F.; Luo, F.-T.; Zhao, F.; Liu, H. Luminescent Probes for Sensitive Detection of pH Changes in Live Cells through Two Near-infrared Luminescence Channels. ACS Sensors, 2017, 2, 924
  3. Zhang, J.; Li, C.; Dutta, C.; Fang, M.; Zhang, S.; Tiwari, A.; Werner, T.; Luo, F.-T.; Liu, H. A Novel Near-infrared Fluorescent Probe for Sensitive Detection of β-Galactosidase in Living Cells. Analytica Chimica Acta, 2017968, 97.
  4. Zhang, S.; Adhikari, R.; Fang, M.; Dorh, N.; Li, C.; Jaishi, M.; Zhang, J.; Tiwari, A.; Pati, R.; Luo, F.-T.; Liu, H. Near-Infrared Fluorescent Probes with Large Stokes Shifts for Sensing Zn(II) Ions in Living Cells. ACS Sensors20161, 1408.
  5. Zhang, J.; Yang, M.; Mazi, W.; Adhikari, K.; Fang, M.; Xie, F.; Valenzano, L.; Tiwari, A.; Luo, F.-T.; Liu, H. Unusual Fluorescent Responses of Morpholine-functionalized Fluorescent Probes to pH via Manipulation of BODIPY’s HOMO and LUMO Energy Orbitals for Intracellular pH Detection. ACS Sensors 20161, 158.
  6. Dorh, N.; Zhu, S.; Dhungana, K. B.; Pati, R.; Luo, F.-T.; Liu, H.; Tiwari, A. BODIPY-Based Fluorescent Probes for Sensing Protein Surface-Hydrophobicity. Sci. Rep. 2015, 5, 18337.
  7. Zhang, J.; Yang, M.; Li, C.; Dorh, N.; Xie, F.; Luo, F.-T.; Tiwari, A.; Liu, H. Near-infrared Fluorescent Probes Based on Piperazine-Functionalized BODIPY Dyes for Sensitive Detection of Lysosomal pH. J. Mater. Chem. B, 2015, 3, 2173.
  8. Vegesna, G. K; Janjanam, J.; Bi, J.; Luo, F.-T.; Zhang, J.; Olds, C.; Tiwari, A.; Liu, H. pH-Activatable Near-Infrared Fluorescent Probes for Detection of Lysosomal pH inside Living Cells. J. Mater. Chem. B, 2014, 2, 4500.
  9. Liu, H.; Vegesna, G.; Sripathi, S.; Zhang, J.; Zhu, S.; Luo, F.-T.; Jahng, W. J.; Frost, M. Highly Water-soluble BODIPY-based Fluorescent Probe for Sensitive and Selective Detection of Nitric Oxide in Living Cells. ACS Applied Materials & Interfaces 2013, 5, 4107.
  10. Zhu, S.; Bi, J.; Vegesna, G.; Zhang, J.; Luo, F.-T.; Valenzano, L.; Liu, H. Functionalization of BODIPY Dyes at 2,6-Positions through Formyl Groups. RSC Adv. 2013, 3, 4793.
  11. Zhu, S.; Zhang, J.; Janjanam, J.; Dorh, N.; Bi, J.; Vegesna, G.; Luo, F.-T.; Tiwari, A.; Liu, H. Highly Water-soluble BODIPY-based Fluorescent Probes for Sensitive Fluorescent Sensing of Zinc(II). J. Mater. Chem. B 2013, 1, 1722.
  12. Zhang, J.; Zhu, S.; Valenzano, L.; Luo, F.-T.; Liu, H. BODIPY-based Ratiometric Fluorescent Probes for Sensitive and Selective Sensing of Cyanide Ion. RSC Adv. 2013, 3, 68.
  13. Zhu, S.; Zhang, J.; Janjanam, J.; Bi, J.; Vegesna, G.; Tiwari, A.; Luo, F.-T.; Wei, J.; Liu, H. Highly Water-soluble, Near-infrared Emissive BODIPY Polymeric Dye Bearing RGD Peptide Residues for Cancer Imaging. Analytica Chimica Acta 2013, 758, 138.
  14. Zhu, S.; Dorh, N.; Zhang, J.; Vegesna, G.; Li, H.; Luo, F.-T.; Tiwari, A.; Liu, H. Highly Water-soluble Neutral Near-infrared Emissive BODIPY Polymeric Dyes. J. Mater. Chem. 2012, 22, 2781.
  15. Lo, H.-K.; Luo, F.-T. Synthesis of PS-supported NHC-Pd catalyst derived from theobromine and its applications in Suzuki-Miyaura reaction. J. Chin. Chem. Soc. 2012, 59, 394.
  16. Zhu, S.; Zhang, J.; Vegesna, G.; Tiwari, A.; Luo, F.-T.; Zeller, M.; Luck, R.; Li, H.; Green, S.; Liu, H.; Controlled Knoevenagel Reactions of Methyl Groups of 1,3,5,7-Tetramethyl BODIPY Dyes for Unique BODIPY Dyes. RSC Adv. 2012, 2, 404.
  17. Zhu, S.; Zhang, J.; Vegesna, G. K.; Pandey, R.; Luo, F.-T.; Green, S.; Liu, H.; One-pot Efficient Synthesis of Dimeric, Trimeric, and Tetrameric BODIPY Dyes. Chem. Commun. 2011, 47, 3508.
  18. Zhu, S.; Zhang, J.; Vegesna, G.; Luo, F.-T.; Green, S.; Liu, H. Highly Water-soluble Neutral BODIPY Dyes with Controllable Fluorescence Quantum Yields. Org. Lett. 2011, 13, 438.
  19. Luo, F.-T.; Lo, H.-K. Synthesis of bis-NHC-Pd catalyst derived from caffeine and its applications in Suzuki, Heck, and Sonogashira reactions. J. Organomet. Chem. 2011, 696, 1262.

Selected Patent:

  1. Frank H. Shu, Fen-Tair Luo, Michael J. Cai, “Batch-Process Supertorrefaction System and Method”, Taiwan Patent, TW I560265, December 1, 2016.
  2. Frank H. Shu, Fen-Tair Luo, Michael J. Cai, “Batch-Process Supertorrefaction System and Method”, USA, Canada, China, Russia, India, Germany, France. WO2015171865 A1, November 12, 2015.
  3. Frank H. Shu, Michael J. Cai, Fen-Tair Luo, “Supertorrefaction of Biomass into Biocoal”, P. R. China Patent, CN 103249817 A, August 26, 2015.
  4. Frank H. Shu, Michael J. Cai, Fen-Tair Luo, “Supertorrefaction of Biomass into Biocoal”, USA Patent, US 9096800, August 4, 2015.
  5. Frank H. Shu, Michael J. Cai, Fen-Tair Luo, "Supertorrefaction of Biomass (Variants)", Russia Patent, No. 2549876, April 3, 2015.
  6. Frank H. Shu, Michael J. Cai, Fen-Tair Luo, “Supertorrefaction of Biomass into Biocoal”, “Supertorrefaction de Biomasse en Biocharbon (French)”, Canada Patent, CA 2807094, March 31, 2015.
  7. Frank H. Shu, Michael J. Cai, Fen-Tair Luo, “Supertorrefaction of Biomass into Biocoal”, Taiwan Patent, TW I443187, July 1, 2014.
  8. Fen-Tair Luo, “Polystyrene-supported Palladacycle Catalysts”, USA Patent, US 7115762 B2, October 3, 2006.

 

Update: 2017-10-18

Journal Paper
  1. Shuwei Zhang, Rashmi Adhikari, Mingxi Fang, Nethaniah Dorh, Cong Li, Meghnath Jaishi, Jingtuo Zhang, Ashutosh Tiwari,* Ranjit Pati,* Fen-Tair Luo,* and Haiying Liu* Near-Infrared Fluorescent Probes with Large Stokes Shifts for Sensing Zn(II) Ions in Living Cells. ACS Sensors 2016-11-171, 1408-1415.
  2. Jianheng Bi, Mingxi Fang, Jianbo Wang,* Shuai Xia, Yibin Zhang, Jingtuo Zhang, Giri Vegesna, Shuwei Zhang, Marina Tanasova,* Fen-Tair Luo,* and Haiying Liu* Near-Infrared Fluorescent Probe for Sensitive Detection of Pb(II) Ions in Living Cells. Inorganica Chimica Acta 2017-11-1468, 140-145.
  3. Shuwei Zhang, Tzu-Ho Chen, Hsien-Ming Lee,* Jianheng Bi, Avik Ghosh, Mingxi Fang, Zichen Qian, Fei Xie, Fen-Tair Luo,* Feng Zhao,* Haiying Liu* Luminescent Probes for Sensitive Detection of pH Changes in Live Cells through Two Near-infrared Luminescence Channels. ACS Sensors 2017-06-272(7), 924-931.
  4. Jingtuo Zhang, Cong Li, Colina Dutta, Mingxi Fang, Shuwei Zhang, Ashutosh Tiwari,* Thomas Werner,* Fen-Tair Luo,* and Haiying Liu* A Novel Near-infrared Fluorescent Probe for Sensitive Detection of beta-Galactosidase in Living Cells. Analytica Chimica Acta 2017-05-22968, 97-104.
  5. Jingtuo Zhang, Mu Yang, Wafa Mazi, Kapil Adhikari, Mingxi Fang, Fei Xie, Loredana Valenzano,* Ashutosh Tiwari,* Fen-Tair Luo,* Haiying Liu* Unusual Fluorescent Responses of Morpholine-functionalized Fluorescent Probes to pH via Manipulation of BODIPY’s HOMO and LUMO Energy Orbitals for Intracellular pH Detection. ACS Sensors 2016-02-261, 158-165.
  6. Nethaniah Dorh, Shilei Zhu, Fen-Tair Luo, Haiying Liu, Ashutosh Tiwari BODIPY-Based Fluorescent Probes for Sensing Protein Surface-Hydrophobicity. Scientific Reports 2015-12-185, 18337.
  7. Jingtuo Zhang, Mu Yang, Cong Li, Nethaniah Dorh, Fei Xie, Fen-Tair Luo, Ashutosh Tiwari, and Haiying Liu Near-infrared Fluorescent Probes Based on Piperazine-Functionalized BODIPY Dyes for Sensitive Detection of Lysosomal pH. J. Mater. Chem. B 2015-023, 2173-2184.
  8. Giri K Vegesna, Jagadeesh Janjanam, Jianheng Bi, Fen-Tair Luo, Jingtuo Zhang, Connor Olds, Ashutosh Tiwari, and Haiying Liu pH-Activatable Near-Infrared Fluorescent Probes for Detection of Lysosomal pH inside Living Cells. J. Mater. Chem. B 2014-062, 4500-4508.
  9. Jingtuo Zhang, Shilei Zhu, Loredana Valenzano, Fen-Tair Luo, Haiying Liu BODIPY-based Ratiometric Fluorescent Probes for Sensitive and Selective Sensing of Cyanide Ion. RSC Adv. 20133, 68-72.
  10. Shilei Zhu, Jianheng Bi, Giri Vegesna, Jingtuo Zhang, Fen-Tair Luo, Loredana Valenzano and Haiying Liu Functionalization of BODIPY Dyes at 2,6-Positions through Formyl Groups. RSC Adv. 20133, 4793-4800.
  11. Liu, Haiying; Vegesna, Giri; Sripathi, Srinivas; Zhang, Jingtuo; Zhu, Shilei; Luo, Fen-Tair; Jahng, Wan Jin; Frost, Megan Highly Water-soluble BODIPY-based Fluorescent Probe for Sensitive and Selective Detection of Nitric Oxide in Living Cells. ACS Applied Materials & Interfaces 20135(10), 4107-4112.
  12. Shilei Zhu, Jingtuo Zhang, Jagadeesh Janjanam, Nethaniah Dorh, Jianheng Bi, Giri Vegesna, Fen-Tair Luo, Ashutosh Tiwari, and Haiying Liu Highly Water-soluble BODIPY-based Fluorescent Probes for Sensitive Fluorescent Sensing of Zinc (II). J. Mater. Chem. B 20131, 1722-1728.
  13. Shilei Zhu, Jingtuo Zhang, Jagadeesh Janjanam, Jianheng Bi, Giri Vegesna, Ashutosh Tiwari, Fen-Tair Luo, Jianjun Wei, and Haiying Liu Highly Water-soluble, Near-infrared Emissive BODIPY Polymeric Dye Bearing RGD Peptide Residues for Cancer Imaging. Analytica Chimica Acta 2013758(1), 138-144.
  14. Shilei Zhu, Jingtuo Zhang, Giri Vegesna, Ashutosh Tiwari, Fen-Tair Luo, Matthias Zeller, Rudy Luck, Haihua Li, Sarah Green and Haiying Liu Controlled Knoevenagel Reactions of Methyl Groups of 1,3,5,7-Tetramethyl BODIPY Dyes for Unique BODIPY Dyes. RSC Adv. 20122, 404-407.
  15. Shilei Zhu, Nethaniah Dorh, Jingtuo Zhang, Giri Vegesna, Haihua Li, Fen-Tair Luo, Ashutosh Tiwari and Haiying Liu Highly Water-soluble Neutral Near-infrared Emissive BODIPY Polymeric Dyes. J. Mater. Chem. 201222, 2781-2790.
  16. Hung-Kun Lo, Fen-Tair Luo Synthesis of PS-supported NHC-Pd catalyst derived from theobromine and its applications in Suzuki-Miyaura reaction. J. Chin. Chem. Soc. 201259(3), 394-398.
  17. Shilei Zhu, Jingtuo Zhang, Giri Vegesna, Fen-Tair Luo, Sarah Green and Haiying Liu Highly Water-soluble Neutral BODIPY Dyes with Controllable Fluorescence Quantum Yields. Organic Letters 201113, 438-441.
  18. Shilei Zhu, Jingtuo Zhang, Giri K. Vegesna, Ravi Pandey, Fen-Tair Luo, Sarah A. Green and Haiying Liu One-pot Efficient Synthesis of Dimeric, Trimeric, and Tetrameric BODIPY Dyes for Panchromatic Absorption. Chemical Communications 201147, 3508-3510.
  19. Fen-Tair Luo, Hung-Kun Lo Short Synthesis of Bis-NHC-Pd Catalyst Derived from Caffeine and Its Applications to Suzuki, Heck, and Sonogashira Reactions. Journal of Organometallic Chemistry 2011696, 1262-1265.
  20. Cuihua Xue, Shi-Hao Kung, Jian-Zhung Wu, Fen-Tair Luo Intramolecular Palladium-Catalyzed Cyclization of Alkenylboronate Prepared from Hydroboration of Terminal Acetylene and Its Application to the Stereoselective Synthesis of (E)-Doxepin. Tetrahedron 200864, 248-254.
  21. Hsien-Ren Liao, Yih-Jiun Lin, Yu-Ma Chou, Fen-Tair Luo, Bo-Cheng Wang Theoretical Study of Optical and Electronic Properties of p-Tterphenyls Containing Cyano Substituents as Promising Light Emitting Materials. Journal of Luminescence 2008128, 1373-1378.
  22. Cuihua Xue, Fen-Tair Luo, Haiying Liu Post-polymerization Functionalization Approach for Highly Water-soluble Well-defined Regioregular Head-to-Tail Glycopolythiophenes. Macromolecules 2007, 6863-6870.
  23. Luo, FT、Ravi, VK Polymer-Bound Palladium Catalyst in Carbon-Carbon Bond Formation. Huaxue 2006, 第64卷第1期,頁1-20.
  24. Xue, CH, Luo, FT, Chen, J and Liu, HY Synthesis and Biosensing Application of Highly Water-soluble and Cross-linkable Poly(p-phenyleneethynylene) Containing Osmium(II) Complex and Aldehyde Groups. Analytica Chimica Acta 2006569(no.1-2), 27-34.
  25. Luo, FT, Ravi, VK and Xue, CH The Novel Reaction of Ketones with o-Oxazoline-substituted Anilines. Tetrahedron 200662(40), 9365-9372.
  26. C.J. Wu, C. Xue, Y.M. Kuo and F.T. Luo Preparation and Photoluminescence of p-Terphenyl Derivatives Containing Cyano Groups. Tetrahedron 200561, 4735-4741.
  27. F.T. Luo, C. Xue, S.L. Ko, Y.D. Shao, J.C. Wu and Y.M. Kuo Preparation of Polystyrene-supported Soluble Palladacycle Catalyst for Heck and Suzuki Reactions. Tetrahedron 200561, 6040-6045.
  28. C. Xue, Z. Chen, Y. Wen, F.T. Luo, J. Chen and H. Liu Synthesis of Ferrocene-grafted Poly(p-phenylene-ethynylene)s and Control of Electro-chemical Behaviors of Their Thin Films. Langmuir 200521, 7860-7865.
  29. C. Xue, Z. Chen, F.T. Luo, K. Palaniappan, D.J. Chesney, J. Liu, J. Chen and H. Liu Synthesis of Water-soluble Electroactive Ferrocene-grafted Poly(p-phenylene-ethynylene) via Phase Transfer and Its Biosensing Application. Biomacromolecules 20056, 1810-1815.
  30. C. Xue and F.T. Luo Novel p-Phenylene-vinylene-dithienylene Type Copolymer: Potential Red-emitting Materials. Synthetic Metals 2004145, 67-73.
  31. Z. Chen, C. Xue, W. Shi, F.T. Luo, S. Green, J. Chen and H. Liu Novel Selective and Sensitive Fluorescent Sensors for Metal Ions Based on Manipulation of Side Chain Compositions of Poly(p-phenylene- ethynylene)s. Analytical Chemistry 200476, 6513-6518.
  32. C. Xue and F.T. Luo* Rapid Syntheses of Oligo(p-phenylene- ethynylene)s via Iterative Convergent Approach.. Tetrahedron 200460, 6285-6294.
  33. C. Xue and F.T. Luo The Synthesis and the X-Ray Structure of 1,4-Bis(2-{4-[2-(4-methylthiophenyl)ethynyl]phenyl}ethynyl)-2,5-dihexyloxybenzene. Journal of the Chinese Chemical Society 200451, 1411-1416.
  34. C. Xue and F.T. Luo Transformation of Amides into Esters by the Use of Chlorotrimethylsilane. Journal of the Chinese Chemical Society 200451, 359-362.
  35. A. A. M. Movahedi, S. Hakimelahi, J. Chamani, G.A. Khodarahmi, F. Hassanzadeh, F.T. Luo, T.W. Ly, K.S. Shia, C.F. Yen, M.L. Jain, R. Kulatheeswaran, C. Xue, M. Pasdar and G.H. Hakimelahi Design, Synthesis, and Anticancer Activity of Phosphonic Acid Diphosphate Derivative of Adenine-containing Butenolide and Its Water Soluble Derivatives of Paclitaxel with High Antitumor Activity. Bioorganic & Medicinal Chemistry 200311, 4303-4313.
  36. C. Xue and F.T. Luo Efficient and Rapid Synthesis of Oligo(p-phenylene-vinylene) via Iterative Coherent Approach. Journal of Organic Chemistry 200368, 4417-4421.
  37. T.Y. Lu, C. Xue and F.T. Luo Palladium-catalyzed Cross-coupling Reaction of Aryldioxaborolane with 2-Bromo-N,N-dimethylacetamide. Tetrahedron Letters 200344, 1587-1590.
  38. F.T. Luo, T.Y. Lu and C. Xue Palladium-catalyzed Stereoselective Synthesis of (E)-beta,gamma-Unsaturated Amides. Tetrahedron Letters 200344, 7249-7251.
  39. C.A. Lin and F.T. Luo Polystyrene-supported Soluble Palladacycle Catalyst as Recyclable Catalyst for Heck, Suzuki, and Sonogashira Reactions. Tetrahedron Letters 200344, 7565-7568.
  40. C. Xue and F.T. Luo Synthesis of Oligo(p-phenylene-vinylene-thienylene)s as Potential Red Light-emitting Materials. Tetrahedron 200359, 5193-5198.
  41. B.C. Wang, J.C. Chang, J.H. Pan, C. Xue and F.T. Luo Theoretical Investigation of Electroluminescent material 1,4-Distyrylbenzene Derivatives. Journal of Molecular Structure (Theochem) 2003636, 81-87.
  42. Gholam Hossein Hakimelahi, Kak-Shan Shia, Cuihua Xue, Shahram Hakimelahi, Ali A. Moosavi-Movahedi, Ali A. Saboury, Ali Khalafi-Nezhad, Mohammad N. Soltani-Rad, Valeriy Osyetrov, Kung-Pern Wang, Jyh-Hsiung Liao and Fen-Tair Luo Design, Synthesis, and Biological Evaluation of a Series of beta-Lactam-Based Prodrugs. Bioorganic & Medicinal Chemistry 200210, 3489-3498.
  43. Fen-Tair Luo, Yu-Tai Tao, Sheng-Li Ko, Chang-Hao Chuen, and Hui Chen Efficient Electroluminescent Material for Light-Emitting Diodes from 1,4-Distyrylbenzene Derivatives. Journal of Materials Chemistry 200212, 47-52.
  44. Tomo Sakanoue, Yasukiyo Ueda, Sheng-Li Ko, and Hui Chen, Fen-Tair Luo Fabrication and Characterization of Orientation-Controlled Alkoxy- and Cyano-Substituted Distyrylbenzene Derivatives in Thin Film. Molecular Crystal and Liquid Crystals 2002377, 153-156.
  45. Cuihua Xue, Fen-Tair Luo Synthesis of p-Phenylene-vinylene-thienylene Oligomers. Heterocycles 200257, 1935-1946.
Chapter of Publication
  1. Chih-An Lin, Fen-Tair Luo, 2004, “Polystyrene-Supported Soluble Palladacycle Catalyst as Recyclable Catalyst for Heck, Suzuki, and Sonogashira Reactions”, editor(s): S. M. Roberts, J. Whittall, P. Mather, and P. McCormack, Catalysts for Fine Chemical Synthesis, Vol. 3, Metal Catalysed Carbon-Carbon Bond-Forming Reactions, pp. 116-125, England: John Wiley & Sons.
  2. Fen-Tair Luo, 2002, “Other -Hetero-Substituted Organometals in Palladium-Catalyzed Cross-Coupling”, editor(s): Ei-ichi Negishi, Handbook of Organopalladium Chemistry for Organic Synthesis, Vol. 1, pp. 673-691, New York: John Wiley & Sons.
Science Report
  1. Tomo Sakanoue, Shuhei Nakatani, Yasukiyo Ueda, Fen-Tair Luo, 2002, “Structure and Optical Properties of Distyrylbenzene/PTFE Double Layer”, Technical Report of IEICE (The Institute of Electronics, Information and Communication Engineers), pp. 47, 1-6.