Yu-Ju Chen

Distinguished Research Fellow, Institute of Chemistry,
Academia Sinica

By integrating innovative mass spectrometry with proteomics, bioinformatics and nanomaterials science, her research reveals molecular mechanisms of major diseases, including cancer, and advances biomarker discovery and precision medicine.

Core Expertise

Proteomics and mass spectrometry

Interdisciplinary Integration

Bioinformatics and nanomaterials

Clinical Translation

Cancer biomarkers and precision medicine

Global Engagement

Cancer Moonshot initiatives

Research & Impact

Research and Academic Impact

From analytical innovation and cancer research to international collaboration, her work builds lasting momentum for precision medicine.

Building Advanced Proteomics Platforms

Her team develops internationally recognized analytical technologies and platforms that accelerate the identification, quantification and integration of protein signals in complex biological samples.

Decoding Molecular Features of Lung Adenocarcinoma

Her landmark proteomic and proteogenomic studies of lung adenocarcinoma in East Asian never-smokers have opened new directions for early detection, precision classification and personalized treatment.

Connecting Global Research Communities

She has advanced Taiwan's participation in global Cancer Moonshot efforts while fostering interdisciplinary collaboration, international exchange and the development of future scientific talent.

Publications

Selected Research Highlights

A lung-shaped molecular constellation titled Decoding the Molecular Constellation of Lung Cancer — Cell, Volume 182, Issue 1

Illustration highlighting the colorectal cancer research project. — Colorectal Cancer Research

Single-cell proteomics (SCP) can reveal cellular phenotypic heterogeneity and cell-specific functional networks underlying biological processes — Nature Communications，Volume 13

A microfluidic chip portrayed as a miniature vessel navigating a molecular nebula and mapping single-cell phosphorylation networks — Advanced Science, Volume 12, Issue 1

Single cells travel through a microfluidic channel and release a colorful molecular spray that is converted into highly sensitive mass spectrometry signals — Analytica Chimica Acta, Volume 1154

A classical East Asian garden lattice becomes transmembrane protein structures, symbolizing the decoding of the cellular membrane — Proteomics, Volume 17, Issues 11–12

Black magnetic nanoparticle cores with gold functional arms selectively capture target molecules and gather under an external magnetic field — Small, Volume 2, Issue 4

Explore More

Videos and Feature Stories

Web Links

Feature Stories

A Scholar Who Embraces Challenges: An Interview with Yu-Ju ChenWomen in Science and Technology Newsletter, Issue 008 Decoding the Protein Language of Life and Leading Taiwan's Cancer MoonshotNTU Center for the Advancement of Science Education From the Protein Universe to the Secrets of CancerCommonHealth

YouTube

Videos

Interdisciplinary Proteomics and World-Class Analytical Technologies for Cancer Research台灣萊雅 L'Oréal Taiwan Discussing the Role of Proteomics in Lung Cancer ResearchTechnology Networks The 69th Academic Award: Research Fellow Yu-Ju ChenMinistry of Education, Taiwan