中央研究院化學研究所

Application of Stimuli-Induced Intramolecular Charge Transfer: Control of Binding

Binding is of fundamental importance to supramolecular assemblies. The ability to modulate binding will enable the design of novel stimulus-responsive molecular assemblies. We employ proton-induced and metal-induced intramolecular charge transfer in donor-bridge-acceptor systems to achieve this goal.

----Weakly distance-dependent binding control achieved----

---Binding Center---

Single Hydrogen Bond

Multiple Hydrogen Bond

---Bridge---

Silole Thiophene

Quinoid Hybrid form

---Reaction Center---

Metalation

Chao, I.; Hwang, T.-S. Angew. Chem. Int. Ed. 2001, 40, 2703-2705.
Hwang, T.-S.; Juan, N.; Chen, H.-Y.; Chen, C.-C.; Lo, S.-J.; Chao, I. Chem. Eur. J. 2004, 10, 1616-1624.
Chen, Y.-H.; Chao, I., unpublished results.
Hsu, M.-Y.; Chao, I., unpublished results.
Chen, C.-C.; Chen, Y.-H.; Chao, I., unpublished results.
Chen, H.-Y.; Chao, I., unpublished results.
Lo, S.-J.; Li, W.-S.; Chen, Y.-H.; Chao, I., unpublished results.
Huang, Y.-Y.; Chang, Y. C., Chao, I., unpublisehed results.