中央研究院化學研究所－人員

紫質及其金屬錯合物(合成、化性、催化、光譜等)
紫質衍生物應用在光動力效應治療癌腫瘤

1. Chang, C. K. Paul Rothemund and S. Ferguson MacDonald, and their Namesake Reactions - the Influence of the Fischer School on my Life in Porphyrin Chemistry. Israel J. Chem. 2015, 55, DOI: 10.1002/ijch.201500043.
2. Zoi, H.-B.; Yang, H.; Liu, Z.-Y.; Mahmood, M. H. R.; Mei, G.-Q.; Liu, H.-Y; Chang, C. K. Iron(IV)-Corrole Catalyzed Stereoselective Olefination of Aldehydes with Ethyl Diazoacetate. Organometallics 2015, 34, 2791
3. Nga, N.-C.; Mahmood, M. H. R.; Liu, H. Y.; Yam, F.; Yeung, L.-L.; Chang, C. K. Appended corrole manganese complexes: Catalysis and axial-ligand effect. Chin. Chem. Lett. 2014, 25, 571-574.
4. Liu, H. Y.; Mahmood, M. H. R.; Qiu, S.-X.; Chang, C.-K. Recent Developments in Manganese Corrole Chemistry. Coord. Chem. Rev. 2013, 257, 1306.
5. Mahmood, M. H. R.; Liu, H. Y.; Wang, H. H.; Jiang, Y. Y.; Chang, C.- K. Unexpected One-Pot Synthesis of A3-Type Unsymmetrical Porphyrin. Tetrahedron Lett. 2013, 54, 5853.
6. Ying, X.; Long, X. Y.; Mahmood, M. H. R.; Hu, Q. Y.; Liu, H. Y.; Chang, C.-K. Second-Order Nonlinear Optical Properties of Corroles: Experimental and Theoretical Investigations. Porphyrins Phthalocyanines 2012, 16, 1276.
7. Xing, B.; Jiang, T.; Bi, W.; Yang, Y.; Li, L.; Ma, M.; Chang, C.-K.; Xu, B.; Yeow, E. K. L. Multifunctional Divalent Vancomycin: the Fluorescent Imaging and Photodynamic Antimicrobial Properties for Drug Resistant Bacteria. Chem. Commun. 2011, 47(5), 1601.
8. Lu, J.; Liu, H. Y.; Shi, L.; Wang, X. L.; Ying, X.; Zhang, L.; Ji, L. N.; Zang, L. Q.; Chang, C.-K. DNA Cleavage Mediated by Water-Soluble Manganese Corrole. Chin. Chem. Lett. 2011, 22(1), 101.
9. Koon, H. K.; Chan, P. S.; Wu, Z. G.; Wong, R. N. S.; Lung, M. L.; Chang, C.-K.; Mak, N. K. Role of Mitogen-Activated Protein Kinase in Zn-Bc-Am Pdt-Induced Apoptosis in Nasopharyngeal Carcinoma Cells. Cell Biochem. Funct. 2010, 28(3), 239.
10. Koon, H.-K.; Lo, K.-W.; Leung, K.-N.; Lung, M. L.; Chang, C. C.-K.; Wong, R. N.-S.; Leung, W.-N.; Mak, N.-K. Photodynamic Therapy-Mediated Modulation of Inflammatory Cytokine Production by Epstein-Barr Virus-Infected Nasopharyngeal Carcinoma Cells. Cell. Mol. Immunol. 2010, 7(4), 323.
11. Shi, L.; Liu, H.-Y.; Shen, H.; Hu, J.; Zhang, G.-L.; Wang, H.; Ji, L. N.; Chang, C.-K.; Jiang, H.-F. Fluorescence Properties of Halogenated Mono-Hydroxyl Corroles: The Heavy-Atom Effects. J. Porphyrins Phthalocyanines 2009, 13(12), 1221.
12. Liu, H.-Y.; Yam, F.; Xie, Y.-T.; Li, X.-Y; Chang, C.-K. A Bulky Bis-pocket Manganese (V)-Oxo Corrole Complex: Observation of Oxygen Atom Transfer between Triply Bonded MnVO and Alkene. J. Am. Chem. Soc. 2009, 131, 12890.
13. Wang, Q.; Yang, Z.; Ma, M.; Chang, C.-K.; Xu, B. High Catalytic Activities of Artificial Peroxidases Based on Supramolecular Hydrogels that Contain Heme Models. Chem. Eur. J. 2008, 14, 5073.
14. Liu, H.-Y.; Lai, T.-S.; Yeung, L.-L.; Chang, C.-K. First Synthesis of Perfluorinated Corrole and Its Mn=O Complex. Org. Lett. 2003, 5, 617.
15. Deng, Y.; Chang, C.-K.; Nocera, D. Facile Synthesis ofβ-Derivatized Porphyrins-Structural Characterization of aβ-β-Bis-Porphyrin. Angew. Chem. Int. Ed. Engle. 2000, 39, 1066.
16. Kessel, D.; Luo, Y.; Deng, Y.; Chang, C.-K. The Role of Sub-cellular Localization in Initiation of Apoptosis by Photodynamic Therapy. Photochem. Photobiol. 1997, 65, 422.
17. Liang, Y.; Chang, C.-K.; Peng, S.-M. Molecular Recognition with C-Clamp Porphyrins: Synthesis, Structural, and Complexation Studies. J. Mol. Recogn. 1996, 9, 149.
18. Chang, C.-K.; Liang, Y.; Aviles, G.; Peng, S.-M. Conformational Control of Intramolecular H-Bonding in Heme Models: Maximal Co(II)-O2Binding in a C-Clamp Porphyrin. J. Am. Chem. Soc. 1995, 117, 4191.
19. Chang, C.-K.; Aviles, G.; Bag, N. Verdoheme-like Oxaporphyrin Formation by Oxygenation of a Co(II) Porphyrinyl Naphthoic Acid. A New Model of Heme Degradation. J. Am. Chem. Soc. 1994, 116, 12127.

Update： 2016-01-06